| Applications: | IHC-P/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HILPDA |
| Gene ID: | 29923 |
| Uniprot ID: | HLPDA_HUMAN |
| Immunogen Region: | 1-63 |
| Immunogen Sequence: | MKHVLNLYLLGVVLTLLSIF VRVMESLEGLLESPSPGTSW TTRSQLANTEPTKGLPDHPS RSM |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-63 of human HILPDA (NP_037464.1). |
| Tissue Specificity | Highly expressed in renal cell carcinoma cells but barely detectable in adjacent normal kidney tissue. Detected in some cervical and endometrial cancers. Expression also detected in fetal kidney with little or no expression observed in normal adult heart, liver, lung, pancreas, prostate or spinal cord (at protein level). |
| Function | Increases intracellular lipid accumulation. Stimulates expression of cytokines including IL6, MIF and VEGFA. Enhances cell growth and proliferation. |
| Protein Name | Hypoxia-Inducible Lipid Droplet-Associated ProteinHypoxia-Inducible Gene 2 Protein |
| Database Links | Reactome: R-HSA-8964572 |
| Cellular Localisation | Lipid DropletSecretedMembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Hypoxia-Inducible Lipid Droplet-Associated Protein antibodyAnti-Hypoxia-Inducible Gene 2 Protein antibodyAnti-HILPDA antibodyAnti-C7orf68 antibodyAnti-HIG2 antibody |
Information sourced from Uniprot.org
