Anti-HHEX antibody (STJ193042)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Hematopoietically-expressed homeobox protein HHEX for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HHEX |
| Gene ID | 3087 |
| Uniprot ID | HHEX_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | HHEX Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor. Activator of WNT-mediated transcription in conjunction with CTNNB1. Establishes anterior identity at two levels.acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL. Inhibits EIF4E-mediated mRNA nuclear export. May play a role in hematopoietic differentiation. |
| Protein Name | Hematopoietically-Expressed Homeobox Protein HhexHomeobox Protein HexHomeobox Protein PrhProline-Rich Homeodomain Protein |
| Database Links | Reactome: R-HSA-9925561 |
| Cellular Localisation | NucleusNuclear BodyCytoplasm |
| Alternative Antibody Names | Anti-Hematopoietically-Expressed Homeobox Protein Hhex antibodyAnti-Homeobox Protein Hex antibodyAnti-Homeobox Protein Prh antibodyAnti-Proline-Rich Homeodomain Protein antibodyAnti-HHEX antibodyAnti-HEX antibodyAnti-PRH antibodyAnti-PRHX antibody |
Information sourced from Uniprot.org