| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal anti-HFE for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | R66-6Q-3 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification: | Affinity Chromatography |
| Dilution Range: | WB 1:500-1:1000 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | HFE |
| Gene ID: | 3077 |
| Uniprot ID: | HFE_HUMAN |
| Immunogen: | A synthesized peptide derived from human HFE |
| Tissue Specificity | Expressed in all tissues tested except brain. |
| Function | Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin. |
| Protein Name | Hereditary Hemochromatosis ProteinHla-H |
| Database Links | Reactome: R-HSA-917977 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Hereditary Hemochromatosis Protein antibodyAnti-Hla-H antibodyAnti-HFE antibodyAnti-HLAH antibody |
Information sourced from Uniprot.org
