| Short Description : | Rabbit polyclonal HEYL (1-100) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HEYL |
| Gene ID: | 26508 |
| Uniprot ID: | HEYL_HUMAN |
| Immunogen Region: | 1-100 |
| Immunogen Sequence: | MKRPKEPSGSDGESDGPIDV GQEGQLSQMARPLSTPSSSQ MQARKKHRGIIEKRRRDRIN SSLSELRRLVPTAFEKQGSS KLEKAEVLQMTVDHLKMLHA |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human HEYL (NP_055386.2). |
| Function | Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6. |
| Protein Name | Hairy/Enhancer-Of-Split Related With Yrpw Motif-Like ProteinHheylClass B Basic Helix-Loop-Helix Protein 33Bhlhb33Hairy-Related Transcription Factor 3Hrt-3Hhrt3 |
| Database Links | Reactome: R-HSA-2122947Reactome: R-HSA-2644606Reactome: R-HSA-2894862Reactome: R-HSA-9013508Reactome: R-HSA-9762293 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Hairy/Enhancer-Of-Split Related With Yrpw Motif-Like Protein antibodyAnti-Hheyl antibodyAnti-Class B Basic Helix-Loop-Helix Protein 33 antibodyAnti-Bhlhb33 antibodyAnti-Hairy-Related Transcription Factor 3 antibodyAnti-Hrt-3 antibodyAnti-Hhrt3 antibodyAnti-HEYL antibodyAnti-BHLHB33 antibodyAnti-HRT3 antibody |
Information sourced from Uniprot.org
