Anti-HERV-K Env/ERVK-6 antibody [2I5/H4] (STJA0019866)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Mouse monoclonal Endogenous Retrovirus Group K Member 6 Env Polyprotein antibody for use in ELISA and WB in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 2I5/H4 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 1.62 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | ERVK-6Uniprot ID=ENK6_HUMAN" |
Additional Info
| Post Translational Modifications | Specific enzymatic cleavages in vivo yield the mature SU and TM proteins. |
| Function | Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its original fusogenic properties. SU mediates receptor recognition. TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane. |
| Protein Name | Endogenous Retrovirus Group K Member 6 Env PolyproteinEnvk2 ProteinEnvelope PolyproteinHerv-K(C7 Envelope ProteinHerv-K(Hml-2.Hom Envelope ProteinHerv-K108 Envelope ProteinHerv-K_7p22.1 Provirus Ancestral Env Polyprotein Cleaved Into - Surface ProteinSu - Transmembrane ProteinTm |
| Cellular Localisation | Transmembrane Protein: Cell MembraneSingle-Pass Type I Membrane ProteinSurface Protein: Cell MembranePeripheral Membrane ProteinThe Surface Protein Is Not Anchored To The MembraneBut Localizes To The Extracellular Surface Through Its Binding To TmEndogenous Retrovirus Group K Member 6 Env Polyprotein: Virion |
| Alternative Antibody Names | Anti-Endogenous Retrovirus Group K Member 6 Env Polyprotein antibodyAnti-Envk2 Protein antibodyAnti-Envelope Polyprotein antibodyAnti-Herv-K(C7 Envelope Protein antibodyAnti-Herv-K(Hml-2.Hom Envelope Protein antibodyAnti-Herv-K108 Envelope Protein antibodyAnti-Herv-K_7p22.1 Provirus Ancestral Env Polyprotein Cleaved Into - Surface Protein antibodyAnti-Su - Transmembrane Protein antibodyAnti-Tm antibodyAnti-ERVK-6 antibodyAnti-ERVK6 antibody |
Information sourced from Uniprot.org