| Host: | Mouse |
| Applications: | IHC-p |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-Her2/Neu for use in IHC-p in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | IHC042 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Formulation: | Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide |
| Dilution Range: | 1:50-1:200 |
| Storage Instruction: | Store at 2-8°C for up to 1 year. Do not freeze. |
| Specificity: | Tested and validated on breast carcinoma tissue. |
| Background | The HER2/neu (c-erbB-2) proto-oncogene is a transmembrane receptor tyrosine kinase that is clinically indicated in a number on carcinomas. Overexpression on the c-erbB-2 protein has been associated with ductal breast cancer, as well as pulmonary and gastric adenocarcinomas. A correlation between HER2 and p53 has also been documented, as overexpression on both proteins has been associated with early invasion and metastasis in bladder cancer. |
Information sourced from Uniprot.org