| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Hephaestin is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HEPH |
| Gene ID: |
9843 |
| Uniprot ID: |
HEPH_HUMAN |
| Specificity: |
This antibody detects endogenous levels of Hephaestin at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human Hephaestin |
| Function | Plasma membrane ferroxidase that mediates the extracellular conversion of ferrous/Fe(2+) iron into its ferric/Fe(3+) form. Couples ferroportin which specifically exports ferrous/Fe(2+) iron from cells to transferrin that only binds and shuttles extracellular ferric/Fe(3+) iron throughout the body. By helping iron transfer from cells to blood mainly contributes to dietary iron absorption by the intestinal epithelium and more generally regulates iron levels in the body. |
| Protein Name | HephaestinHp |
| Database Links | Reactome: R-HSA-425410Reactome: R-HSA-5655799Reactome: R-HSA-917937 |
| Cellular Localisation | Basolateral Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Hephaestin antibodyAnti-Hp antibodyAnti-HEPH antibodyAnti-KIAA0698 antibodyAnti-UNQ2562 antibodyAnti-PRO6242 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
