Anti-HEPACAM antibody (10-90 aa) (STJ192481)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 10-90
General Information
| Short Description | Rabbit polyclonal anti-Hepatic and glial cell adhesion molecule (10-90 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HEPACAM |
| Gene ID | 220296 |
| Uniprot ID | HECAM_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 10-90 |
| Immunogen Region | 10-90 aa |
| Specificity | HECAM Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation. In glia, associates and targets CLCN2 at astrocytic processes and myelinated fiber tracts where it may regulate transcellular chloride flux involved in neuron excitability. |
| Protein Name | Hepatic And Glial Cell Adhesion MoleculeGlialcamHepatocyte Cell Adhesion MoleculeProtein Hepacam |
| Database Links | |
| Cellular Localisation | CytoplasmCell MembraneSingle-Pass Type I Membrane ProteinCytoplasmic SideColocalizes With Clcn2 At Astrocyte End-Foot In Contact With Brain Capillaries And Other Glial CellsIn Mcf-7 Breast Carcinoma And Hepatic Hep 3b21-7 And Hep-G2 Cell LinesLocalization Of Hepacam Is Cell Density-DependentIn Well Spread CellsLocalized To Punctate Structures In The Perinuclear MembraneAnd At Cell Surface Of ProtusionsIn Confluent CellsLocalized Predominantly To The Cytoplasmic MembraneParticularly In Areas Of Cell-Cell ContactsColocalizes With Cdh1 |
| Alternative Antibody Names | Anti-Hepatic And Glial Cell Adhesion Molecule antibodyAnti-Glialcam antibodyAnti-Hepatocyte Cell Adhesion Molecule antibodyAnti-Protein Hepacam antibodyAnti-HEPACAM antibody |
Information sourced from Uniprot.org