Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Hepatic and glial cell adhesion molecule (10-90 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
HEPACAM |
Gene ID: |
220296 |
Uniprot ID: |
HECAM_HUMAN |
Immunogen Region: |
10-90 aa |
Specificity: |
HECAM Polyclonal Antibody detects endogenous levels of protein. |
Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 10-90 |
Function | Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation. In glia, associates and targets CLCN2 at astrocytic processes and myelinated fiber tracts where it may regulate transcellular chloride flux involved in neuron excitability. |
Protein Name | Hepatic And Glial Cell Adhesion MoleculeGlialcamHepatocyte Cell Adhesion MoleculeProtein Hepacam |
Cellular Localisation | CytoplasmCell MembraneSingle-Pass Type I Membrane ProteinCytoplasmic SideColocalizes With Clcn2 At Astrocyte End-Foot In Contact With Brain Capillaries And Other Glial CellsIn Mcf-7 Breast Carcinoma And Hepatic Hep 3b21-7 And Hep-G2 Cell LinesLocalization Of Hepacam Is Cell Density-DependentIn Well Spread CellsLocalized To Punctate Structures In The Perinuclear MembraneAnd At Cell Surface Of ProtusionsIn Confluent CellsLocalized Predominantly To The Cytoplasmic MembraneParticularly In Areas Of Cell-Cell ContactsColocalizes With Cdh1 |
Alternative Antibody Names | Anti-Hepatic And Glial Cell Adhesion Molecule antibodyAnti-Glialcam antibodyAnti-Hepatocyte Cell Adhesion Molecule antibodyAnti-Protein Hepacam antibodyAnti-HEPACAM antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance