| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Hepatic and glial cell adhesion molecule (10-90 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HEPACAM |
| Gene ID: | 220296 |
| Uniprot ID: | HECAM_HUMAN |
| Immunogen Region: | 10-90 aa |
| Specificity: | HECAM Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 10-90 |
| Function | Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation. In glia, associates and targets CLCN2 at astrocytic processes and myelinated fiber tracts where it may regulate transcellular chloride flux involved in neuron excitability. |
| Protein Name | Hepatic And Glial Cell Adhesion Molecule Glialcam Hepatocyte Cell Adhesion Molecule Protein Hepacam |
| Cellular Localisation | Cytoplasm Cell Membrane Single-Pass Type I Membrane Protein Cytoplasmic Side Colocalizes With Clcn2 At Astrocyte End-Foot In Contact With Brain Capillaries And Other Glial Cells In Mcf-7 Breast Carcinoma And Hepatic Hep 3b2 1-7 And Hep-G2 Cell Lines Localization Of Hepacam Is Cell Density-Dependent In Well Spread Cells Localized To Punctate Structures In The Perinuclear Membrane And At Cell Surface Of Protusions In Confluent Cells Localized Predominantly To The Cytoplasmic Membrane Particularly In Areas Of Cell-Cell Contacts Colocalizes With Cdh1 |
| Alternative Antibody Names | Anti-Hepatic And Glial Cell Adhesion Molecule antibody Anti-Glialcam antibody Anti-Hepatocyte Cell Adhesion Molecule antibody Anti-Protein Hepacam antibody Anti-HEPACAM antibody |
Information sourced from Uniprot.org