| Host: | Rabbit |
| Applications: | IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal anti-Hemoglobin subunit alpha for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Purification: | Affinity Purified |
| Dilution Range: | IHC 1:100-1:200 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | HBA1.HBA2 |
| Gene ID: | 3039/3040 |
| Uniprot ID: | HBA_HUMAN |
| Immunogen: | A synthesized peptide derived from human Hemoglobin subunit alpha |
| Tissue Specificity | Red blood cells. |
| Post Translational Modifications | The initiator Met is not cleaved in variant Thionville and is acetylated. |
| Function | Involved in oxygen transport from the lung to the various peripheral tissues. Hemopressin: Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1. Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling. |
| Protein Name | Hemoglobin Subunit AlphaAlpha-GlobinHemoglobin Alpha Chain Cleaved Into - Hemopressin |
| Database Links | Reactome: R-HSA-1237044Reactome: R-HSA-1247673Reactome: R-HSA-2168880Reactome: R-HSA-9707564Reactome: R-HSA-9707616 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Hemoglobin Subunit Alpha antibodyAnti-Alpha-Globin antibodyAnti-Hemoglobin Alpha Chain Cleaved Into - Hemopressin antibodyAnti-HBA1.HBA2 antibody |
Information sourced from Uniprot.org