Anti-HELZ2 antibody (1909-1958 aa) (STJ95222)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human PRIC285 at the amino acid range 1909-1958
General Information
| Short Description | Rabbit polyclonal anti-Helicase with zinc finger domain 2 (1909-1958 aa) for use in WB, ELISA and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA/IHC |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HELZ2 |
| Gene ID | 85441 |
| Uniprot ID | HELZ2_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human PRIC285 at the amino acid range 1909-1958 |
| Immunogen Region | 1909-1958 aa |
| Specificity | PRIC285 Polyclonal Antibody detects endogenous levels of PRIC285 protein. |
Additional Info
| Function | Can degrade highly structured RNAs through its concerted ATP-dependent RNA helicase and 3' to 5' exoribonuclease activities. Shows a strong preference for pyrimidine over purine residues for its nuclease activity. Acts as a transcriptional coactivator for a number of nuclear receptors including PPARA, PPARG, THRA, THRB and RXRA. |
| Protein Name | 3'-5' Exoribonuclease Helz2Atp-Dependent Rna Helicase Pric285Helicase With Zinc Finger 2 - Transcriptional CoactivatorHelicase With Zinc Finger Domain 2Ppar-Alpha-Interacting Complex Protein 285Ppar-Gamma Dna-Binding Domain-Interacting Protein 1Pdip1Ppar-Gamma Dbd-Interacting Protein 1Peroxisomal Proliferator-Activated Receptor A-Interacting Complex 285 Kda Protein |
| Database Links | Reactome: R-HSA-1368082Reactome: R-HSA-1368108Reactome: R-HSA-1989781Reactome: R-HSA-2151201Reactome: R-HSA-2426168Reactome: R-HSA-381340Reactome: R-HSA-400206Reactome: R-HSA-400253Reactome: R-HSA-9707564Reactome: R-HSA-9707616 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-3'-5' Exoribonuclease Helz2 antibodyAnti-Atp-Dependent Rna Helicase Pric285 antibodyAnti-Helicase With Zinc Finger 2 - Transcriptional Coactivator antibodyAnti-Helicase With Zinc Finger Domain 2 antibodyAnti-Ppar-Alpha-Interacting Complex Protein 285 antibodyAnti-Ppar-Gamma Dna-Binding Domain-Interacting Protein 1 antibodyAnti-Pdip1 antibodyAnti-Ppar-Gamma Dbd-Interacting Protein 1 antibodyAnti-Peroxisomal Proliferator-Activated Receptor A-Interacting Complex 285 Kda Protein antibodyAnti-HELZ2 antibodyAnti-KIAA1769 antibodyAnti-PRIC285 antibody |
Information sourced from Uniprot.org