| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HEATR1 |
| Gene ID: |
55127 |
| Uniprot ID: |
HEAT1_HUMAN |
| Immunogen Region: |
1-120 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human HEATR1 (NP_060542.4). |
| Immunogen Sequence: |
MTSLAQQLQRLALPQSDASL LSRDEVASLLFDPKEAATID RDTAFAIGCTGLEELLGIDP SFEQFEAPLFSQLAKTLERS VQTKAVNKQLDENISLFLIH LSPYFLLKPAQKCLEWLIHR |
| Function | Ribosome biogenesis factor.required for recruitment of Myc to nucleoli. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in neuronal-lineage cell proliferation. |
| Protein Name | Heat Repeat-Containing Protein 1Protein Bap28U3 Small Nucleolar Rna-Associated Protein 10 Homolog Cleaved Into - Heat Repeat-Containing Protein 1 - N-Terminally Processed |
| Database Links | Reactome: R-HSA-6790901Reactome: R-HSA-6791226 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-Heat Repeat-Containing Protein 1 antibodyAnti-Protein Bap28 antibodyAnti-U3 Small Nucleolar Rna-Associated Protein 10 Homolog Cleaved Into - Heat Repeat-Containing Protein 1 - N-Terminally Processed antibodyAnti-HEATR1 antibodyAnti-BAP28 antibodyAnti-UTP10 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
