Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Mouse/Rat/Monkey |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Polyamine deacetylase HDAC10 (10-59 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
HDAC10 |
Gene ID: |
83933 |
Uniprot ID: |
HDA10_HUMAN |
Immunogen Region: |
10-59 aa |
Specificity: |
Histone deacetylase 10 Polyclonal Antibody detects endogenous levels of Histone deacetylase 10 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human HDAC10 at the amino acid range 10-59 |
Function | Polyamine deacetylase (PDAC), which acts preferentially on N(8)-acetylspermidine, and also on acetylcadaverine and acetylputrescine. Exhibits attenuated catalytic activity toward N(1),N(8)-diacetylspermidine and very low activity, if any, toward N(1)-acetylspermidine. Histone deacetylase activity has been observed in vitro. Has also been shown to be involved in MSH2 deacetylation. The physiological relevance of protein/histone deacetylase activity is unclear and could be very weak. May play a role in the promotion of late stages of autophagy, possibly autophagosome-lysosome fusion and/or lysosomal exocytosis in neuroblastoma cells. May play a role in homologous recombination. May promote DNA mismatch repair. |
Protein Name | Polyamine Deacetylase Hdac10Histone Deacetylase 10Hd10 |
Database Links | Reactome: R-HSA-2122947Reactome: R-HSA-2644606Reactome: R-HSA-2894862Reactome: R-HSA-3214815Reactome: R-HSA-350054 |
Cellular Localisation | CytoplasmNucleusExcluded From Nucleoli |
Alternative Antibody Names | Anti-Polyamine Deacetylase Hdac10 antibodyAnti-Histone Deacetylase 10 antibodyAnti-Hd10 antibodyAnti-HDAC10 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance