Anti-HCV subtype 1b NS5B protein antibody (1-14 aa) [8B2] (STJA0002824)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenRecombinant Hepatitis C Virus subtype 1b nonstructural protein 5B (NS5B) RNA-dependent RNA polymerase (RdRp). Mapped to amino acids 1-14 (SMSYTWTGALITPC)
General Information
| Short Description | Mouse monoclonal anti-HCV subtype 1b NS5B protein (1-14 aa) for use in ELISA and IP in Human and HCV samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/IP |
| Host | Mouse |
| Reactivity | Human/HCV |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 8B2 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Purification | NA Protein G purification NA |
| Dilution Range | Very weak antigen recognition in WBOptimal conditions for IP should be determined for each particular application Blocks the RNA-dependent RNA polymerase activity in vitro. Monoclonal antibody working titer has to be established practically for each |
| Formulation | PBS pH 7.4, with 0.1% sodium azide |
| Storage Instruction | Store at-20 to-70 °C upon receipt. Divide antibody into aliquots prior usage. Avoid multiple freeze-thaw cycles as product degradation may result. |
Target Information
| Immunogen | Recombinant Hepatitis C Virus subtype 1b nonstructural protein 5B (NS5B) RNA-dependent RNA polymerase (RdRp). Mapped to amino acids 1-14 (SMSYTWTGALITPC) |
| Immunogen Region | 1-14 aa |
| Specificity | Human, HCV subtype 1b NS5B, Epitope mapped to amino acids 1-14 (SMSYTWTGALITPC) |
Additional Info
| Background | Non-structural protein 5B (NS5B) represents the RNA-dependent RNA polymerase (RdRp) of Hepatitis C Virus, which is a small positive strand RNA virus in the family Flaviviridae. HCV is a major causative agent of acute and chronic hepatitis, hepatocellular carcinoma and liver cirrhosis. The single subunit RNA-dependent RNA polymerase is absolutely essential for the viral replication. |
Information sourced from Uniprot.org