Anti-HCN3 antibody [SAA0501] (STJA0019344)

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STJA0019344
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Short Description :Mouse monoclonal Potassium/Sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 3 antibody for use in IF, IHC and WB in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IF/IHC/WB
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Clonality :Monoclonal
Clone ID :SAA0501
Isotype:IgG2a
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:Protein A/G purified from cell culture supernatant
Formulation:0.01M PBS, pH 7.4.
Storage Instruction:Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol:HCN3
Gene ID:57657
Uniprot ID:HCN3_HUMAN
Function Hyperpolarization-activated ion channel that are permeable to sodium and potassium ions, with an about 3:1 preference for potassium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). In particular, plays a pivotal role in maintaining excitability and promoting rhythmic burst firing within hypothalamic nuclei. Exerts a significant influence on the configuration of the cardiac action potential waveform. Does not appear to play a prominent role in the processing of acute, neuropathic, or inflammatory pain.
Protein Name Potassium/Sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 3
Database Links Reactome: R-HSA-1296061
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Potassium/Sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 3 antibody
Anti-HCN3 antibody
Anti-KIAA1535 antibody

Information sourced from Uniprot.org

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