| Short Description : | Rabbit polyclonal anti-Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (380-460 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HCN1 |
| Gene ID: | 348980 |
| Uniprot ID: | HCN1_HUMAN |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 380-460 |
| Immunogen Region: | 380-460 aa |
| Specificity: | HCN1 Polyclonal Antibody detects endogenous levels of protein. |
| Function | Hyperpolarization-activated ion channel that are permeable to sodium and potassium ions. Displays lower selectivity for K(+) over Na(+) ions. Contributes to the native pacemaker currents in heart (If) and in the generation of the I(h) current which controls neuron excitability. Participates in cerebellar mechanisms of motor learning. May mediate responses to sour stimuli. |
| Protein Name | Potassium/Sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 1Brain Cyclic Nucleotide-Gated Channel 1Bcng-1 |
| Database Links | Reactome: R-HSA-1296061 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Potassium/Sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 1 antibodyAnti-Brain Cyclic Nucleotide-Gated Channel 1 antibodyAnti-Bcng-1 antibodyAnti-HCN1 antibodyAnti-BCNG1 antibody |
Information sourced from Uniprot.org
