Anti-hCG beta antibody [5006] (STJ400082)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenBeta-2 as described in Berger et al. (2013). The antibody recognizes both intact hCG and free ß subunit.
General Information
| Short Description | Mouse monoclonal anti-hCG beta for use in CLIA and FIA in hCG beta samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | CLIA/FIA |
| Host | Mouse |
| Reactivity | hCG beta |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 5006 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 5.0 mg/ml (+/-10 %) |
| Formulation | 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Storage Instruction | Store at 2–8 °C, and do not freeze. |
Target Information
| Immunogen | Beta-2 as described in Berger et al. (2013). The antibody recognizes both intact hCG and free ß subunit. |
| Specificity | Antibody recognizes human chorionic gonadotropin and its free beta subunit. LH (KD = 24 nM). Does not recognize hCGa, FSH, or TSH |
Additional Info
| Tissue Specificity | High expression in the placenta throughout pregnancy. |
| Function | Beta subunit of the human chorionic gonadotropin (hCG). hCG is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. The alpha subunit is identical to those in the pituitary gonadotropin hormones (LH, FSH and TSH). The beta subunits are distinct in each of the hormones and confer receptor and biological specificity. Has an essential role in pregnancy and maternal adaptation. Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. |
| Protein Name | Choriogonadotropin Subunit Beta 3Choriogonadotropin Subunit BetaCg-BetaChorionic Gonadotropin Chain Beta |
| Database Links | Reactome: R-HSA-209822Reactome: R-HSA-8866910 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Choriogonadotropin Subunit Beta 3 antibodyAnti-Choriogonadotropin Subunit Beta antibodyAnti-Cg-Beta antibodyAnti-Chorionic Gonadotropin Chain Beta antibodyAnti-CGB3 antibodyAnti-CGB.CGB5.CGB8 antibody |
Information sourced from Uniprot.org