| Short Description : | Mouse monoclonal anti-HbA1c (N-Term) for use in FIA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | FIA |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | 2403 |
| Isotype: | IgG1 |
| Conjugation: | Unconjugated |
| Concentration: | 5.0 mg/ml (+/-10 %) |
| Formulation: | 50 mM citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Storage Instruction: | Store at 2–8 °C, and do not freeze. |
| Immunogen: | N-terminal end of the beta chain |
| Immunogen Region: | N-Term |
| Specificity: | Antibody recognizes human glycated hemoglobin A1. Does not recognize non-glycated hemoglobin A1. |
| Background | Glycated hemoglobin (HbA1c) is formed in a non-enzymatic process during exposure to plasma glucose. Normal levels of glucose produce a normal amount of glycated hemoglobin. As the average amount of plasma glucose increases, the fraction of glycated hemoglobin increases in a predictable way. This serves as a marker for average blood glucose levels over the previous months prior to the measurement. The 2010 American Diabetes Association Standards of Medical Care in Diabetes added the HbA1c ≥ 48 mmol/mol (≥ 6.5 %) as another criterion for the diagnosis of diabetes. |
Information sourced from Uniprot.org
