| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-HAS1 (80-390) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HAS1 |
| Gene ID: |
3036 |
| Uniprot ID: |
HYAS1_HUMAN |
| Immunogen Region: |
80-390 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 80-390 of human HAS1 (NP_001514.2). |
| Immunogen Sequence: |
RVAAAARGPLDAATARSVAL TISAYQEDPAYLRQCLASAR ALLYPRARLRVLMVVDGNRA EDLYMVDMFREVFADEDPAT YVWDGNYHQPWEPAAAGAVG AGAYREVEAEDPGRLAVEAL VRTRRCVCVAQRWGGKREVM YTAFKALGDSVDYVQVCDSD TRLDPMALLELVRVLDEDPR VGAVGGDVRILNPLDSWVSF LSSLRYWVAFNVERACQSYF HCVSCISGPLGLYRNNLLQ |
| Tissue Specificity | Widely expressed. Highly expressed in ovary followed by spleen, thymus, prostate, testes and large intestine. Weakly expressed in small intestine. |
| Function | Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction. Also able to catalyze the synthesis of chito-oligosaccharide depending on the substrate. |
| Protein Name | Hyaluronan Synthase 1Hyaluronate Synthase 1Hyaluronic Acid Synthase 1Ha Synthase 1Huhas1 |
| Database Links | Reactome: R-HSA-2142850 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Hyaluronan Synthase 1 antibodyAnti-Hyaluronate Synthase 1 antibodyAnti-Hyaluronic Acid Synthase 1 antibodyAnti-Ha Synthase 1 antibodyAnti-Huhas1 antibodyAnti-HAS1 antibodyAnti-HAS antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
