| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HARS2 |
| Gene ID: | 23438 |
| Uniprot ID: | SYHM_HUMAN |
| Immunogen Region: | 217-506 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 217-506 of human HARS2 (NP_036340.1). |
| Immunogen Sequence: | IVDGMFAVCGVPESKFRAIC SSIDKLDKMAWKDVRHEMVV KKGLAPEVADRIGDYVQCHG GVSLVEQMFQDPRLSQNKQA LEGLGDLKLLFEYLTLFGIA DKISFDLSLARGLDYYTGVI YEAVLLQTPTQAGEEPLNVG SVAAGGRYDGLVGMFDPKGH KVPCVGLSIGVERIFYIVEQ RMKTKGEKVRTTETQVFVAT PQKNFLQERLKLIAELWDSG IKAEMLYKNNPKLLTQLHY |
| Tissue Specificity | A high level expression is seen in the heart, kidney and skeletal muscle while a lower level expression is seen in the brain and liver. |
| Function | Mitochondrial aminoacyl-tRNA synthetase that catalyzes the ATP-dependent ligation of histidine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (His-AMP). |
| Protein Name | Histidine--Trna Ligase - MitochondrialHistidine--Trna Ligase-LikeHistidyl-Trna SynthetaseHisrs |
| Database Links | Reactome: R-HSA-379726 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Histidine--Trna Ligase - Mitochondrial antibodyAnti-Histidine--Trna Ligase-Like antibodyAnti-Histidyl-Trna Synthetase antibodyAnti-Hisrs antibodyAnti-HARS2 antibodyAnti-HARSL antibodyAnti-HARSR antibodyAnti-HO3 antibody |
Information sourced from Uniprot.org