Anti-HAND2 antibody (1-100) {Biotin} (STJ501311)

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STJ501311-100
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: ELISA/IHC/IP/WB
Reactivity: Human/Monkey/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-HAND2 (1-100) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality : Polyclonal
Conjugation: Biotin
Isotype: IgG
Formulation: Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Purification: Affinity Purified
Concentration: 0.53-0.63 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:200
IHC: 1:100
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Hand2
Gene ID: 64637
Uniprot ID: HAND2_RAT
Immunogen Region: 1-100
Immunogen: Synthetic peptide taken within amino acid region 1-100 on Human HAND2 protein.
Function Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Also plays an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3'.
Protein Name Heart- And Neural Crest Derivatives-Expressed Protein 2
Deciduum - Heart - Autonomic Nervous System And Neural Crest Derivatives-Expressed Protein 2
Dhand
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Heart- And Neural Crest Derivatives-Expressed Protein 2 antibody
Anti-Deciduum - Heart - Autonomic Nervous System And Neural Crest Derivatives-Expressed Protein 2 antibody
Anti-Dhand antibody
Anti-Hand2 antibody
Anti-Dhand antibody

Information sourced from Uniprot.org

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