| Short Description : | Rabbit polyclonal anti-2-hydroxyacyl-CoA lyase 1 (323-373 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HACL1 |
| Gene ID: | 26061 |
| Uniprot ID: | HACL1_HUMAN |
| Immunogen: | Synthesized peptide derived from the human HACL1 at the amino acid range 323-373 |
| Immunogen Region: | 323-373 aa |
| Specificity: | This antibody detects endogenous levels of HACL1 at Human/Mouse/Rat |
| Function | Peroxisomal 2-OH acyl-CoA lyase involved in the cleavage (C1 removal) reaction in the fatty acid alpha-oxydation in a thiamine pyrophosphate (TPP)-dependent manner. Involved in the degradation of 3-methyl-branched fatty acids like phytanic acid and the shortening of 2-hydroxy long-chain fatty acids. Plays a significant role in the biosynthesis of heptadecanal in the liver. |
| Protein Name | 2-Hydroxyacyl-Coa Lyase 12-Hydroxyphytanoyl-Coa Lyase2-HpclPhytanoyl-Coa 2-Hydroxylase 2 |
| Database Links | Reactome: R-HSA-389599Reactome: R-HSA-9033241 |
| Cellular Localisation | Peroxisome |
| Alternative Antibody Names | Anti-2-Hydroxyacyl-Coa Lyase 1 antibodyAnti-2-Hydroxyphytanoyl-Coa Lyase antibodyAnti-2-Hpcl antibodyAnti-Phytanoyl-Coa 2-Hydroxylase 2 antibodyAnti-HACL1 antibodyAnti-HPCL antibodyAnti-HPCL2 antibodyAnti-PHYH2 antibodyAnti-HSPC279 antibody |
Information sourced from Uniprot.org
