Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-2-hydroxyacyl-CoA lyase 1 (323-373 aa) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
HACL1 |
Gene ID: |
26061 |
Uniprot ID: |
HACL1_HUMAN |
Immunogen Region: |
323-373 aa |
Specificity: |
This antibody detects endogenous levels of HACL1 at Human/Mouse/Rat |
Immunogen: |
Synthesized peptide derived from the human HACL1 at the amino acid range 323-373 |
Function | Peroxisomal 2-OH acyl-CoA lyase involved in the cleavage (C1 removal) reaction in the fatty acid alpha-oxydation in a thiamine pyrophosphate (TPP)-dependent manner. Involved in the degradation of 3-methyl-branched fatty acids like phytanic acid and the shortening of 2-hydroxy long-chain fatty acids. Plays a significant role in the biosynthesis of heptadecanal in the liver. |
Protein Name | 2-Hydroxyacyl-Coa Lyase 12-Hydroxyphytanoyl-Coa Lyase2-HpclPhytanoyl-Coa 2-Hydroxylase 2 |
Database Links | Reactome: R-HSA-389599Reactome: R-HSA-9033241 |
Cellular Localisation | Peroxisome |
Alternative Antibody Names | Anti-2-Hydroxyacyl-Coa Lyase 1 antibodyAnti-2-Hydroxyphytanoyl-Coa Lyase antibodyAnti-2-Hpcl antibodyAnti-Phytanoyl-Coa 2-Hydroxylase 2 antibodyAnti-HACL1 antibodyAnti-HPCL antibodyAnti-HPCL2 antibodyAnti-PHYH2 antibodyAnti-HSPC279 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance