| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Putative histone H2B type 2-C (82-132 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:1000-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | H2BC20P |
| Uniprot ID: | H2B2C_HUMAN |
| Immunogen Region: | 82-132 aa |
| Specificity: | This antibody detects endogenous levels of human H2B2C |
| Immunogen: | Synthesized peptide derived from the human H2B2C at the amino acid range 82-132 |
| Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Protein Name | Putative Histone H2b Type 2-CH2b-Clustered Histone 20 PseudogeneHistone H2b.tH2b/T |
| Cellular Localisation | NucleusChromosome |
| Alternative Antibody Names | Anti-Putative Histone H2b Type 2-C antibodyAnti-H2b-Clustered Histone 20 Pseudogene antibodyAnti-Histone H2b.t antibodyAnti-H2b/T antibodyAnti-H2BC20P antibodyAnti-HIST2H2BC antibody |
Information sourced from Uniprot.org