| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Histone H2B type 1-C/E/F/G/I is suitable for use in Western Blot and ELISA research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | H2BC4.H2BC6.H2BC7.H2BC8.H2BC10 |
| Gene ID: | 3017/8339/8343/8344/8346/8347 |
| Uniprot ID: | H2B1C_HUMAN |
| Specificity: | H2B1C Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from part of the human protein |
| Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid. |
| Protein Name | Histone H2b Type 1-C/E/F/G/IHistone H2b.1 AHistone H2b.aH2b/AHistone H2b.gH2b/GHistone H2b.hH2b/HHistone H2b.kH2b/KHistone H2b.lH2b/L |
| Database Links | Reactome: R-HSA-110328Reactome: R-HSA-110329Reactome: R-HSA-110330Reactome: R-HSA-110331Reactome: R-HSA-1221632Reactome: R-HSA-171306Reactome: R-HSA-1912408Reactome: R-HSA-201722Reactome: R-HSA-212300Reactome: R-HSA-2299718Reactome: R-HSA-2559580Reactome: R-HSA-2559582Reactome: R-HSA-2559586Reactome: R-HSA-3214815Reactome: R-HSA-3214847Reactome: R-HSA-427359Reactome: R-HSA-427389Reactome: R-HSA-427413Reactome: R-HSA-5250924Reactome: R-HSA-5334118Reactome: R-HSA-5578749Reactome: R-HSA-5617472Reactome: R-HSA-5625886Reactome: R-HSA-5689880Reactome: R-HSA-5693565Reactome: R-HSA-5693571Reactome: R-HSA-5693607Reactome: R-HSA-606279Reactome: R-HSA-68616Reactome: R-HSA-69473Reactome: R-HSA-73728Reactome: R-HSA-73772Reactome: R-HSA-8866654Reactome: R-HSA-8936459Reactome: R-HSA-8939236Reactome: R-HSA-9018519Reactome: R-HSA-912446Reactome: R-HSA-9609690Reactome: R-HSA-9610379Reactome: R-HSA-9616222Reactome: R-HSA-9670095Reactome: R-HSA-9710421Reactome: R-HSA-977225 |
| Cellular Localisation | NucleusChromosome |
| Alternative Antibody Names | Anti-Histone H2b Type 1-C/E/F/G/I antibodyAnti-Histone H2b.1 A antibodyAnti-Histone H2b.a antibodyAnti-H2b/A antibodyAnti-Histone H2b.g antibodyAnti-H2b/G antibodyAnti-Histone H2b.h antibodyAnti-H2b/H antibodyAnti-Histone H2b.k antibodyAnti-H2b/K antibodyAnti-Histone H2b.l antibodyAnti-H2b/L antibodyAnti-H2BC4 antibodyAnti-H2BFL antibodyAnti-HIST1H2BC.H2BC6 antibodyAnti-H2BFH antibodyAnti-HIST1H2BE.H2BC7 antibodyAnti-H2BFG antibodyAnti-HIST1H2BF.H2BC8 antibodyAnti-H2BFA antibodyAnti-HIST1H2BG.H2BC10 antibodyAnti-H2BFK antibodyAnti-HIST1H2BI antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
