| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | H2-Ab1 |
| Uniprot ID: | HB2S_MOUSE |
| Immunogen Region: | 30-219 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-219 of mouse H2-Ab1 (NP_996988.2). |
| Immunogen Sequence: | SERHFVYQFMGECYFTNGTQ RIRYVTRYIYNREEYVRYDS DVGEHRAVTELGRPDAEYWN SQPEILERTRAELDTVCRHN YEGPETHTSLRRLEQPNVVI SLSRTEALNHHNTLVCSVTD FYPAKIKVRWFRNGQEETVG VSSTQLIRNGDWTFQVLVML EMTPRRGEVYTCHVEHPSLK SPITVEWRAQ |
| Post Translational Modifications | Ubiquitinated in immature dendritic cells leading to down-regulation of MHC class II. |
| Protein Name | H-2 Class Ii Histocompatibility Antigen - A-S Beta Chain |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-H-2 Class Ii Histocompatibility Antigen - A-S Beta Chain antibodyAnti-H2-Ab1 antibody |
Information sourced from Uniprot.org