| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Glycogen synthase, liver (26-76) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GYS2 |
| Gene ID: |
2998 |
| Uniprot ID: |
GYS2_HUMAN |
| Immunogen Region: |
26-76 |
| Specificity: |
This antibody detects endogenous levels of human GYS2 |
| Immunogen: |
Synthesized peptide derived from human GYS2 AA range: 26-76 |
| Post Translational Modifications | Primed phosphorylation at Ser-657 (site 5) by CSNK2A1 and CSNK2A2 is required for inhibitory phosphorylation at Ser-641 (site 3a), Ser-645 (site 3b), Ser-649 (site 3c) and Ser-653 (site 4) by GSK3A an GSK3B. Dephosphorylation at Ser-641 and Ser-645 by PP1 activates the enzyme. Phosphorylation at Ser-8 is not required for interaction with GYG1. Interaction with GYG1 does not regulate the phosphorylation at Ser-8 and Ser-641. |
| Function | Glycogen synthase participates in the glycogen biosynthetic process along with glycogenin and glycogen branching enzyme. Extends the primer composed of a few glucose units formed by glycogenin by adding new glucose units to it. In this context, glycogen synthase transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan. |
| Protein Name | Glycogen Starch Synthase - LiverGlycogen Synthase 2 |
| Database Links | Reactome: R-HSA-3322077Reactome: R-HSA-3858516Reactome: R-HSA-3878781 |
| Alternative Antibody Names | Anti-Glycogen Starch Synthase - Liver antibodyAnti-Glycogen Synthase 2 antibodyAnti-GYS2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
