Anti-GUCY2D antibody (52-350) (STJ23897)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GUCY2D (52-350) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GUCY2D |
| Gene ID | 3000 |
| Uniprot ID | GUC2D_HUMAN |
| Immunogen Region | 52-350 |
| Immunogen Sequence | AVFTVGVLGPWACDPIFSRA RPDLAARLAAARLNRDPGLA GGPRFEVALLPEPCRTPGSL GAVSSALARVSGLVGPVNPA ACRPAELLAEEAGIALVPWG CPWTQAEGTTAPAVTPAADA LYALLRAFGWARVALVTAPQ DLWVEAGRSLSTALRARGLP VASVTSMEPLDLSGAREALR KVRDGPRVTAVIMVMHSVLL GGEEQRYLLEAAEELGLTDG SLVFLPFDTIHYALSPGPE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 52-350 of human GUCY2D (NP_000171.1). |
Additional Info
| Tissue Specificity | Retina. |
| Function | Catalyzes the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors. Plays an essential role in phototransduction, by mediating cGMP replenishment. May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane. |
| Protein Name | Retinal Guanylyl Cyclase 1Retgc-1Cg-EGuanylate Cyclase 2d - RetinalRod Outer Segment Membrane Guanylate CyclaseRos-Gc |
| Database Links | Reactome: R-HSA-2514859 |
| Cellular Localisation | Photoreceptor Outer Segment MembraneSingle-Pass Type I Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Retinal Guanylyl Cyclase 1 antibodyAnti-Retgc-1 antibodyAnti-Cg-E antibodyAnti-Guanylate Cyclase 2d - Retinal antibodyAnti-Rod Outer Segment Membrane Guanylate Cyclase antibodyAnti-Ros-Gc antibodyAnti-GUCY2D antibodyAnti-CORD6 antibodyAnti-GUC1A4 antibodyAnti-GUC2D antibodyAnti-RETGC antibodyAnti-RETGC1 antibody |
Information sourced from Uniprot.org