Anti-GUCY2C antibody [SAA0124] {FITC} (STJA0028356)

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STJA0028356
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Covered by St John's Laboratory Guarantee

Host: Human
Applications: FC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Human monoclonal antibody anti-Guanylyl Cyclase C is suitable for use in Flow Cytometry research applications.
Clonality : Monoclonal
Clone ID : SAA0124
Conjugation: FITC
Isotype: IgG1k
Formulation: 0.01M PBS, pH 7.4, 02% BSA, 0.05% Proclin 300
Purification: Purified
Concentration: 05 mg/mL
Storage Instruction: Store at 4°C for 12 months Protect from light Do not freeze
Gene Symbol: GUCY2C
Gene ID: 2984
Uniprot ID: GUC2C_HUMAN
Function Guanylyl cyclase that catalyzes synthesis of cyclic GMP (cGMP) from GTP. Receptor for the E.coli heat-stable enterotoxin.E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GUCY2C. Also activated by the endogenous peptides guanylin and uroguanylin.
Protein Name Guanylyl Cyclase C
Gc-C
Heat-Stable Enterotoxin Receptor
Sta Receptor
Hstar
Intestinal Guanylate Cyclase
Database Links Reactome: R-HSA-8935690
Reactome: R-HSA-8942233
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Endoplasmic Reticulum Membrane
The 145 Kda Plasma Membrane Form Of Gucy2c Contains Sialic Acid And Galactose Residues
While A Differencially Glycosylated 130 Kda Form Is A High Mannose Form That Is Resident In The Endoplasmic Reticulum And May Serve As The Precursor For The Cell Surface Form
Alternative Antibody Names Anti-Guanylyl Cyclase C antibody
Anti-Gc-C antibody
Anti-Heat-Stable Enterotoxin Receptor antibody
Anti-Sta Receptor antibody
Anti-Hstar antibody
Anti-Intestinal Guanylate Cyclase antibody
Anti-GUCY2C antibody
Anti-GUC2C antibody
Anti-STAR antibody

Information sourced from Uniprot.org

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