| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Guanylate cyclase activator 2B (1-50 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GUCA2B |
| Gene ID: | 2981 |
| Uniprot ID: | GUC2B_HUMAN |
| Immunogen Region: | 1-50 aa |
| Specificity: | GUC2B Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from part of the human protein at the amino acid range 1-50 |
| Function | Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport. |
| Protein Name | Guanylate Cyclase Activator 2b Cleaved Into - Guanylate Cyclase C-Activating Peptide 2 Guanylate Cyclase C-Activating Peptide Ii Gcap-Ii - Uroguanylin Ugn |
| Database Links | Reactome: R-HSA-8935690 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Guanylate Cyclase Activator 2b Cleaved Into - Guanylate Cyclase C-Activating Peptide 2 antibody Anti-Guanylate Cyclase C-Activating Peptide Ii antibody Anti-Gcap-Ii - Uroguanylin antibody Anti-Ugn antibody Anti-GUCA2B antibody |
Information sourced from Uniprot.org