| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GUCA2A (22-115) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GUCA2A |
| Gene ID: |
2980 |
| Uniprot ID: |
GUC2A_HUMAN |
| Immunogen Region: |
22-115 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 22-115 of human GUCA2A (NP_291031.2). |
| Immunogen Sequence: |
VTVQDGNFSFSLESVKKLKD LQEPQEPRVGKLRNFAPIPG EPVVPILCSNPNFPEELKPL CKEPNAQEILQRLEEIAEDP GTCEICAYAACTGC |
| Tissue Specificity | Highly expressed in ileum and colon. Found in plasma. |
| Function | Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. |
| Protein Name | GuanylinGuanylate Cyclase Activator 2aGuanylate Cyclase-Activating Protein 1Guanylate Cyclase-Activating Protein IGcap-I Cleaved Into - Hmw-Guanylin - Guanylin |
| Database Links | Reactome: R-HSA-8935690 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Guanylin antibodyAnti-Guanylate Cyclase Activator 2a antibodyAnti-Guanylate Cyclase-Activating Protein 1 antibodyAnti-Guanylate Cyclase-Activating Protein I antibodyAnti-Gcap-I Cleaved Into - Hmw-Guanylin - Guanylin antibodyAnti-GUCA2A antibodyAnti-GUCA2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and CDK2AP1 knockout (KO) 293T cells, using [KO Validated] CDK2AP1 Rabbit polyclonal antibody (STJ11100861) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/89795/358264/STJ11100861_1__24480.1713122604.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and CDK2AP1 knockout (KO) 293T cells, using [KO Validated] CDK2AP1 Rabbit polyclonal antibody (STJ11100861) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.")
