| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GUCA2A |
| Gene ID: | 2980 |
| Uniprot ID: | GUC2A_HUMAN |
| Immunogen Region: | 22-115 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-115 of human GUCA2A (NP_291031.2). |
| Immunogen Sequence: | VTVQDGNFSFSLESVKKLKD LQEPQEPRVGKLRNFAPIPG EPVVPILCSNPNFPEELKPL CKEPNAQEILQRLEEIAEDP GTCEICAYAACTGC |
| Tissue Specificity | Highly expressed in ileum and colon. Found in plasma. |
| Function | Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. |
| Protein Name | GuanylinGuanylate Cyclase Activator 2aGuanylate Cyclase-Activating Protein 1Guanylate Cyclase-Activating Protein IGcap-I Cleaved Into - Hmw-Guanylin - Guanylin |
| Database Links | Reactome: R-HSA-8935690 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Guanylin antibodyAnti-Guanylate Cyclase Activator 2a antibodyAnti-Guanylate Cyclase-Activating Protein 1 antibodyAnti-Guanylate Cyclase-Activating Protein I antibodyAnti-Gcap-I Cleaved Into - Hmw-Guanylin - Guanylin antibodyAnti-GUCA2A antibodyAnti-GUCA2 antibody |
Information sourced from Uniprot.org