| Function | GTPase component of the GTPBP3-MTO1 complex that catalyzes the 5-taurinomethyluridine (taum(5)U) modification at the 34th wobble position (U34) of mitochondrial tRNAs (mt-tRNAs), which plays a role in mt-tRNA decoding and mitochondrial translation. Taum(5)U formation on mammalian mt-tRNA requires the presence of both GTPBP3-mediated GTPase activity and MTO1 catalytic activity. |
| Protein Name | 5-Taurinomethyluridine-Trna Synthase Subunit Gtpb3 - MitochondrialGtp-Binding Protein 3Mitochondrial Gtp-Binding Protein 1Trna Modification Gtpase Gtpbp3 - Mitochondrial |
| Database Links | Reactome: R-HSA-6787450 |
| Cellular Localisation | MitochondrionIsoform 4: Cytoplasm |
| Alternative Antibody Names | Anti-5-Taurinomethyluridine-Trna Synthase Subunit Gtpb3 - Mitochondrial antibodyAnti-Gtp-Binding Protein 3 antibodyAnti-Mitochondrial Gtp-Binding Protein 1 antibodyAnti-Trna Modification Gtpase Gtpbp3 - Mitochondrial antibodyAnti-GTPBP3 antibodyAnti-MTGP1 antibody |
Information sourced from Uniprot.org
