Anti-GTF2IRD1 antibody (Internal) (STJ70971)

SKU:
STJ70971-100
£312.50
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Host: Goat
Applications: Pep-ELISA/WB/IF/FC
Reactivity: Human/Mouse/Rat/Dog
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Goat polyclonal antibody anti-GTF2IRD1 (Internal) is suitable for use in ELISA, Western Blot, Immunofluorescence and Flow Cytometry research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: Peptide ELISA: antibody detection limit dilution 1:64000.
WB: Approx 110kDa band observed in nuclear lysates of cell line Jurkat (calculated MW of 106kDa according to NP_057412.1). Recommended concentration: 0.5-1µg/ml. Primary incubation 1 hour
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: GTF2IRD1
Gene ID: 9569
Uniprot ID: GT2D1_HUMAN
Immunogen Region: Internal
Accession Number: NP_057412.1; NP_005676.3; NP_001186136.1
Immunogen Sequence: NKFTKDTTKLEPAS
Function May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8.
Protein Name General Transcription Factor Ii-I Repeat Domain-Containing Protein 1
Gtf2i Repeat Domain-Containing Protein 1
General Transcription Factor Iii
Mustrd1/Ben
Muscle Tfii-I Repeat Domain-Containing Protein 1
Slow-Muscle-Fiber Enhancer-Binding Protein
Use B1-Binding Protein
Williams-Beuren Syndrome Chromosomal Region 11 Protein
Williams-Beuren Syndrome Chromosomal Region 12 Protein
Cellular Localisation Nucleus
Alternative Antibody Names Anti-General Transcription Factor Ii-I Repeat Domain-Containing Protein 1 antibody
Anti-Gtf2i Repeat Domain-Containing Protein 1 antibody
Anti-General Transcription Factor Iii antibody
Anti-Mustrd1/Ben antibody
Anti-Muscle Tfii-I Repeat Domain-Containing Protein 1 antibody
Anti-Slow-Muscle-Fiber Enhancer-Binding Protein antibody
Anti-Use B1-Binding Protein antibody
Anti-Williams-Beuren Syndrome Chromosomal Region 11 Protein antibody
Anti-Williams-Beuren Syndrome Chromosomal Region 12 Protein antibody
Anti-GTF2IRD1 antibody
Anti-CREAM1 antibody
Anti-GTF3 antibody
Anti-MUSTRD1 antibody
Anti-RBAP2 antibody
Anti-WBSCR11 antibody
Anti-WBSCR12 antibody

Information sourced from Uniprot.org