| Tissue Specificity | Highly expressed in adult skeletal muscle, heart, fibroblast, bone and fetal tissues. Expressed at lower levels in all other tissues tested. |
| Function | May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8. |
| Protein Name | General Transcription Factor Ii-I Repeat Domain-Containing Protein 1Gtf2i Repeat Domain-Containing Protein 1General Transcription Factor IiiMustrd1/BenMuscle Tfii-I Repeat Domain-Containing Protein 1Slow-Muscle-Fiber Enhancer-Binding ProteinUse B1-Binding ProteinWilliams-Beuren Syndrome Chromosomal Region 11 ProteinWilliams-Beuren Syndrome Chromosomal Region 12 Protein |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-General Transcription Factor Ii-I Repeat Domain-Containing Protein 1 antibodyAnti-Gtf2i Repeat Domain-Containing Protein 1 antibodyAnti-General Transcription Factor Iii antibodyAnti-Mustrd1/Ben antibodyAnti-Muscle Tfii-I Repeat Domain-Containing Protein 1 antibodyAnti-Slow-Muscle-Fiber Enhancer-Binding Protein antibodyAnti-Use B1-Binding Protein antibodyAnti-Williams-Beuren Syndrome Chromosomal Region 11 Protein antibodyAnti-Williams-Beuren Syndrome Chromosomal Region 12 Protein antibodyAnti-GTF2IRD1 antibodyAnti-CREAM1 antibodyAnti-GTF3 antibodyAnti-MUSTRD1 antibodyAnti-RBAP2 antibodyAnti-WBSCR11 antibodyAnti-WBSCR12 antibody |
Information sourced from Uniprot.org
![Immunoprecipitation analysis of 300 Mu g extracts of U-87 cells using 3 Mu g [KO Validated] ZMYND8 Rabbit polyclonal antibody (STJ11104587). Western blot was performed from the immunoprecipitate using [KO Validated] ZMYND8 Rabbit polyclonal antibody (STJ11104587) at a dilition of 1:1000.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/177231/368825/STJ11104587_1__31783.1713134287.jpg?c=1 "Immunoprecipitation analysis of 300 Mu g extracts of U-87 cells using 3 Mu g [KO Validated] ZMYND8 Rabbit polyclonal antibody (STJ11104587). Western blot was performed from the immunoprecipitate using [KO Validated] ZMYND8 Rabbit polyclonal antibody (STJ11104587) at a dilition of 1:1000.")
