Anti-GTF2IRD1 antibody (660-959) (STJ28696)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GTF2IRD1 (660-959) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GTF2IRD1 |
| Gene ID | 9569 |
| Uniprot ID | GT2D1_HUMAN |
| Immunogen Region | 660-959 |
| Immunogen Sequence | SLGFSPPALPPERDSGDPLV DESLKRQGFQENYDARLSRI DIANTLREQVQDLFNKKYGE ALGIKYPVQVPYKRIKSNPG SVIIEGLPPGIPFRKPCTFG SQNLERILAVADKIKFTVTR PFQGLIPKPDEDDANRLGEK VILREQVKELFNEKYGEALG LNRPVLVPYKLIRDSPDAVE VTGLPDDIPFRNPNTYDIHR LEKILKAREHVRMVIINQLQ PFAEICNDAKVPAKDSSIP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 660-959 of human GTF2IRD1 (NP_057412.1). |
Additional Info
| Tissue Specificity | Highly expressed in adult skeletal muscle, heart, fibroblast, bone and fetal tissues. Expressed at lower levels in all other tissues tested. |
| Function | May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8. |
| Protein Name | General Transcription Factor Ii-I Repeat Domain-Containing Protein 1Gtf2i Repeat Domain-Containing Protein 1General Transcription Factor IiiMustrd1/BenMuscle Tfii-I Repeat Domain-Containing Protein 1Slow-Muscle-Fiber Enhancer-Binding ProteinUse B1-Binding ProteinWilliams-Beuren Syndrome Chromosomal Region 11 ProteinWilliams-Beuren Syndrome Chromosomal Region 12 Protein |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-General Transcription Factor Ii-I Repeat Domain-Containing Protein 1 antibodyAnti-Gtf2i Repeat Domain-Containing Protein 1 antibodyAnti-General Transcription Factor Iii antibodyAnti-Mustrd1/Ben antibodyAnti-Muscle Tfii-I Repeat Domain-Containing Protein 1 antibodyAnti-Slow-Muscle-Fiber Enhancer-Binding Protein antibodyAnti-Use B1-Binding Protein antibodyAnti-Williams-Beuren Syndrome Chromosomal Region 11 Protein antibodyAnti-Williams-Beuren Syndrome Chromosomal Region 12 Protein antibodyAnti-GTF2IRD1 antibodyAnti-CREAM1 antibodyAnti-GTF3 antibodyAnti-MUSTRD1 antibodyAnti-RBAP2 antibodyAnti-WBSCR11 antibodyAnti-WBSCR12 antibody |
Information sourced from Uniprot.org