Anti-GTF2A1 antibody (1-270) (STJ27298)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GTF2A1 (1-270) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GTF2A1 |
| Gene ID | 2957 |
| Uniprot ID | TF2AA_HUMAN |
| Immunogen Region | 1-270 |
| Immunogen Sequence | MANSANTNTVPKLYRSVIED VINDVRDIFLDDGVDEQVLM ELKTLWENKLMQSRAVDGFH SEEQQLLLQVQQQHQPQQQQ HHHHHHHQQAQPQQTVPQQA QTQQVLIPASQQATAPQVIV PDSKLIQHMNASNMSAAATA ATLALPAGVTPVQQILTNSG QLLQVVRAANGAQYIFQPQQ SVVLQQQVIPQMQPGGVQAP VIQQVLAPLPGGISPQTGVI IQPQQILFTGNKTQVIPTT |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human GTF2A1 (NP_056943.1). |
Additional Info
| Post Translational Modifications | The alpha and beta subunits are postranslationally produced from the precursor form by TASP1. The cleavage promotes proteasomal degradation. |
| Function | TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity. |
| Protein Name | Transcription Initiation Factor Iia Subunit 1General Transcription Factor Iia Subunit 1TfiialTranscription Initiation Factor Tfiia 42 Kda SubunitTfiia-42 Cleaved Into - Transcription Initiation Factor Iia Alpha ChainTfiia P35 Subunit - Transcription Initiation Factor Iia Beta ChainTfiia P19 Subunit |
| Database Links | Reactome: R-HSA-167161Reactome: R-HSA-167162Reactome: R-HSA-167172Reactome: R-HSA-674695Reactome: R-HSA-6807505Reactome: R-HSA-73776Reactome: R-HSA-73779Reactome: R-HSA-75953Reactome: R-HSA-76042Reactome: R-HSA-9018519 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Initiation Factor Iia Subunit 1 antibodyAnti-General Transcription Factor Iia Subunit 1 antibodyAnti-Tfiial antibodyAnti-Transcription Initiation Factor Tfiia 42 Kda Subunit antibodyAnti-Tfiia-42 Cleaved Into - Transcription Initiation Factor Iia Alpha Chain antibodyAnti-Tfiia P35 Subunit - Transcription Initiation Factor Iia Beta Chain antibodyAnti-Tfiia P19 Subunit antibodyAnti-GTF2A1 antibodyAnti-TF2A1 antibody |
Information sourced from Uniprot.org