Anti-GSTA1 antibody (1-222) (STJ11100222)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GSTA1 (1-222) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GSTA1 |
| Gene ID | 2938 |
| Uniprot ID | GSTA1_HUMAN |
| Immunogen Region | 1-222 |
| Immunogen Sequence | MAEKPKLHYFNARGRMESTR WLLAAAGVEFEEKFIKSAED LDKLRNDGYLMFQQVPMVEI DGMKLVQTRAILNYIASKYN LYGKDIKERALIDMYIEGIA DLGEMILLLPVCPPEEKDAK LALIKEKIKNRYFPAFEKVL KSHGQDYLVGNKLSRADIHL VELLYYVEELDSSLISSFPL LKALKTRISNLPTVKKFLQP GSPRKPPMDEKSLEEARKIF RF |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-222 of human GSTA1 (NP_665683.1). |
Additional Info
| Tissue Specificity | Liver. |
| Function | Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds (Probable). Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). It also catalyzes the isomerization of D5-androstene-3,17-dione (AD) into D4-androstene-3,17-dione and may therefore play an important role in hormone biosynthesis. Through its glutathione-dependent peroxidase activity toward the fatty acid hydroperoxide (13S)-hydroperoxy-(9Z,11E)-octadecadienoate/13-HPODE it is also involved in the metabolism of oxidized linoleic acid. |
| Protein Name | Glutathione S-Transferase A113-Hydroperoxyoctadecadienoate PeroxidaseAndrost-5-Ene-3 -17-Dione IsomeraseGst Ha Subunit 1Gst Class-Alpha Member 1Gst-EpsilonGsta1-1Gth1 Cleaved Into - Glutathione S-Transferase A1 - N-Terminally Processed |
| Database Links | Reactome: R-HSA-156590Reactome: R-HSA-189483Reactome: R-HSA-9748787Reactome: R-HSA-9818027 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Glutathione S-Transferase A1 antibodyAnti-13-Hydroperoxyoctadecadienoate Peroxidase antibodyAnti-Androst-5-Ene-3 -17-Dione Isomerase antibodyAnti-Gst Ha Subunit 1 antibodyAnti-Gst Class-Alpha Member 1 antibodyAnti-Gst-Epsilon antibodyAnti-Gsta1-1 antibodyAnti-Gth1 Cleaved Into - Glutathione S-Transferase A1 - N-Terminally Processed antibodyAnti-GSTA1 antibody |
Information sourced from Uniprot.org