Anti-GSR antibody (423-522) [S4MR] (STJ11102104)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal GLUR (423-522) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S4MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:6000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GSR |
| Gene ID | 2936 |
| Uniprot ID | GSHR_HUMAN |
| Immunogen Region | 423-522 |
| Immunogen Sequence | TVGLTEDEAIHKYGIENVKT YSTSFTPMYHAVTKRKTKCV MKMVCANKEEKVVGIHMQGL GCDEMLQGFAVAVKMGATKA DFDNTVAIHPTSSEELVTLR |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 423-522 of human GSR (P00390). |
Additional Info
| Function | Catalyzes the reduction of glutathione disulfide (GSSG) to reduced glutathione (GSH). Constitutes the major mechanism to maintain a high GSH:GSSG ratio in the cytosol. |
| Protein Name | Glutathione Reductase - MitochondrialGrGrase |
| Database Links | Reactome: R-HSA-2408550 P00390-2Reactome: R-HSA-3299685Reactome: R-HSA-499943 P00390-2Reactome: R-HSA-5628897 P00390-2Reactome: R-HSA-9818027 P00390-2 |
| Cellular Localisation | Isoform Mitochondrial: MitochondrionIsoform Cytoplasmic: Cytoplasm |
| Alternative Antibody Names | Anti-Glutathione Reductase - Mitochondrial antibodyAnti-Gr antibodyAnti-Grase antibodyAnti-GSR antibodyAnti-GLUR antibodyAnti-GRD1 antibody |
Information sourced from Uniprot.org