Anti-GSR antibody (273-522) (STJ113969)

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STJ113969
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Short Description :Rabbit polyclonal GSR (273-522) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/ELISA
Host:Rabbit
Reactivity:Human/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:GSR
Gene ID:2936
Uniprot ID:GSHR_HUMAN
Immunogen Region:273-522
Immunogen Sequence:MISTNCTEELENAGVEVLKF SQVKEVKKTLSGLEVSMVTA VPGRLPVMTMIPDVDCLLWA IGRVPNTKDLSLNKLGIQTD DKGHIIVDEFQNTNVKGIYA VGDVCGKALLTPVAIAAGRK LAHRLFEYKEDSKLDYNNIP TVVFSHPPIGTVGLTEDEAI HKYGIENVKTYSTSFTPMYH AVTKRKTKCVMKMVCANKEE KVVGIHMQGLGCDEMLQGFA VAVKMGATKADFDNTVAIH
Specificity:Recombinant fusion protein containing a sequence corresponding to amino acids 273-522 of human GSR (NP_000628.2).
Function Catalyzes the reduction of glutathione disulfide (GSSG) to reduced glutathione (GSH). Constitutes the major mechanism to maintain a high GSH:GSSG ratio in the cytosol.
Protein Name Glutathione Reductase - Mitochondrial
Gr
Grase
Database Links Reactome: R-HSA-2408550 P00390-2
Reactome: R-HSA-3299685
Reactome: R-HSA-499943 P00390-2
Reactome: R-HSA-5628897 P00390-2
Reactome: R-HSA-9818027 P00390-2
Cellular Localisation Isoform Mitochondrial: Mitochondrion
Isoform Cytoplasmic: Cytoplasm
Alternative Antibody Names Anti-Glutathione Reductase - Mitochondrial antibody
Anti-Gr antibody
Anti-Grase antibody
Anti-GSR antibody
Anti-GLUR antibody
Anti-GRD1 antibody

Information sourced from Uniprot.org