Anti-GSN nanobody [SAA1179] (STJN000109)

Anti-GSN nanobody [SAA1179] (STJN000109)

SKU:
STJN000109
£378.50 - £1,632.50
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Host: Alpaca
Applications: ELISA/IF
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Alpaca monoclonal nanobody anti-Gelsolin is suitable for use in ELISA and Immunofluorescence research applications.
Clonality : Monoclonal
Clone ID : SAA1179
Conjugation: Unconjugated
Isotype: VHH-8His-Cys-tag
Formulation: 0.01M PBS, pH 7.4.
Purification: Purified by Nickel column.
Concentration: 1 mg/mL
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.
Gene Symbol: GSN
Gene ID: 2934
Uniprot ID: GELS_HUMAN
Post Translational Modifications Phosphorylation on Tyr-86, Tyr-409, Tyr-465, Tyr-603 and Tyr-651 in vitro is induced in presence of phospholipids.
Function Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.
Protein Name Gelsolin
Agel
Actin-Depolymerizing Factor
Adf
Brevin
Database Links Reactome: R-HSA-264870
Reactome: R-HSA-6798695
Reactome: R-HSA-9662361
Reactome: R-HSA-977225
Cellular Localisation Isoform 2: Cytoplasm
Cytoskeleton
Isoform 1: Secreted
Alternative Nanobody Names Anti-Gelsolin nanobody
Anti-Agel nanobody
Anti-Actin-Depolymerizing Factor nanobody
Anti-Adf nanobody
Anti-Brevin nanobody
Anti-GSN nanobody

Information sourced from Uniprot.org

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