| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat/Bovine/Canine/Human/Non-Human Primates/Zebrafish |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-mGluR7 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol. |
| Purification: |
This antibody was antigen affinity purified from serum. |
| Dilution Range: |
WB 1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
Grm7 |
| Gene ID: |
81672 |
| Uniprot ID: |
GRM7_RAT |
| Immunogen: |
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser862 conjugated to KLH. |
| Tissue Specificity | Widely distributed throughout the brain. |
| Function | G-protein coupled receptor activated by glutamate that regulates axon outgrowth through the MAPK-cAMP-PKA signaling pathway during neuronal development. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase that it inhibits. |
| Protein Name | Metabotropic Glutamate Receptor 7Mglur7 |
| Database Links | Reactome: R-RNO-418594Reactome: -RNO-420499 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Metabotropic Glutamate Receptor 7 antibodyAnti-Mglur7 antibodyAnti-Grm7 antibodyAnti-Gprc1g antibodyAnti-Mglur7 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
