| Host: | Goat |
| Applications: | Pep-ELISA/IF |
| Reactivity: | Human/Mouse/Rat/Dog |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-GRIN2A (211-224) is suitable for use in ELISA and Immunofluorescence research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:16000.IF: Strong expression of the protein seen in the plasma membrane of NIH3T3 cells. Recommended concentration: 10µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | GRIN2A |
| Gene ID: | 2903 |
| Uniprot ID: | NMDE1_HUMAN |
| Immunogen Region: | 211-224 |
| Accession Number: | NP_000824.1; NP_001127880.1 |
| Specificity: | This antibody is expected to recognize both reported isoforms (NP_000824.1; NP_001127880.1). The immunizing peptide represents part of an extra-cellular domain. Reported variants represent identical protein: NP_001127879.1, NP_000824.1 |
| Immunogen Sequence: | EDAKTQVQLKKIHS |
| Protein Name | Glutamate Receptor Ionotropic - Nmda 2aGlun2aGlutamate Nmda Receptor Subunit Epsilon-1N-Methyl D-Aspartate Receptor Subtype 2aNmdar2aNr2aHnr2a |
| Database Links | Reactome: R-HSA-438066Reactome: R-HSA-6794361Reactome: R-HSA-8849932Reactome: R-HSA-9022699Reactome: R-HSA-9609736Reactome: R-HSA-9617324Reactome: R-HSA-9620244 |
| Cellular Localisation | Cell ProjectionDendritic SpineCell MembraneMulti-Pass Membrane ProteinSynapsePostsynaptic Cell MembraneCytoplasmic Vesicle MembraneExpression At The Dendrite Cell Membrane And At Synapses Is Regulated By Sorcs2 And The Retromer Complex |
| Alternative Antibody Names | Anti-Glutamate Receptor Ionotropic - Nmda 2a antibodyAnti-Glun2a antibodyAnti-Glutamate Nmda Receptor Subunit Epsilon-1 antibodyAnti-N-Methyl D-Aspartate Receptor Subtype 2a antibodyAnti-Nmdar2a antibodyAnti-Nr2a antibodyAnti-Hnr2a antibodyAnti-GRIN2A antibodyAnti-NMDAR2A antibody |
Information sourced from Uniprot.org
