Western blot analysis of various lysates, using Glutathione Peroxidase 2 Rabbit monoclonal antibody (STJ11103822) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.

Anti-GPX2 antibody (70-174) [S3822RM] (STJ11103822)

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STJ11103822
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Monoclonal
Clone ID : S3822RM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GPX2
Gene ID: 2877
Uniprot ID: GPX2_HUMAN
Immunogen Region: 70-174
Specificity: A synthetic peptide corresponding to a sequence within amino acids 70-174 of human Glutathione Peroxidase 2 (NP_002074.2).
Immunogen Sequence: QFGHQENCQNEEILNSLKYV RPGGGYQPTFTLVQKCEVNG QNEHPVFAYLKDKLPYPYDD PFSLMTDPKLIIWSPVRRSD VAWNFEKFLIGPEGEPFRRY SRTFP
Tissue Specificity Mostly in liver and gastrointestinal tract, not found in heart or kidney.
Function Catalyzes the reduction of hydroperoxides in a glutathione-dependent manner thus regulating cellular redox homeostasis. Can reduce small soluble hydroperoxides such as H2O2, cumene hydroperoxide and tert-butyl hydroperoxide, as well as several fatty acid-derived hydroperoxides. Cannot reduce phosphatidycholine hydroperoxide.
Protein Name Glutathione Peroxidase 2
Gpx-2
Gshpx-2
Gastrointestinal Glutathione Peroxidase
Glutathione Peroxidase-Gastrointestinal
Gpx-Gi
Gshpx-Gi
Glutathione Peroxidase-Related Protein 2
Gprp-2
Phospholipid Hydroperoxide Glutathione Peroxidase Gpx2
Database Links Reactome: R-HSA-2142688
Reactome: R-HSA-2142712
Reactome: R-HSA-2142770
Reactome: R-HSA-3299685
Reactome: R-HSA-5628897
Cellular Localisation Cytoplasm
Cytosol
Alternative Antibody Names Anti-Glutathione Peroxidase 2 antibody
Anti-Gpx-2 antibody
Anti-Gshpx-2 antibody
Anti-Gastrointestinal Glutathione Peroxidase antibody
Anti-Glutathione Peroxidase-Gastrointestinal antibody
Anti-Gpx-Gi antibody
Anti-Gshpx-Gi antibody
Anti-Glutathione Peroxidase-Related Protein 2 antibody
Anti-Gprp-2 antibody
Anti-Phospholipid Hydroperoxide Glutathione Peroxidase Gpx2 antibody
Anti-GPX2 antibody

Information sourced from Uniprot.org

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