Anti-GPSM2 antibody (STJ190839)

SKU:
STJ190839

Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-G-protein-signaling modulator 2 is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GPSM2
Gene ID: 29899
Uniprot ID: GPSM2_HUMAN
Specificity: GPSM2 Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from part of the human protein
Function Plays an important role in mitotic spindle pole organization via its interaction with NUMA1. Required for cortical dynein-dynactin complex recruitment during metaphase. Plays a role in metaphase spindle orientation. Also plays an important role in asymmetric cell divisions. Has guanine nucleotide dissociation inhibitor (GDI) activity towards G(i) alpha proteins, such as GNAI1 and GNAI3, and thereby regulates their activity.
Protein Name G-Protein-Signaling Modulator 2
Mosaic Protein Lgn
Database Links Reactome: R-HSA-418594
Cellular Localisation Cytoplasm
Cell Cortex
Cytoskeleton
Spindle Pole
Lateral Cell Membrane
Localizes In The Cytoplasm During Interphase And At Cell Cortex During Metaphase
Colocalizes With Numa1 To Mitotic Spindle Poles
Localized At The Central And Lateral Cell Cortex Regions In A Rangtp-Dependent Manner
In Horizontally Retinal Progenitor Dividing Cells
Localized To The Lateral Cortical Region
In Vertically Retinal Progenitor Dividing Cells
Localized At The Polar Cortical Region
Alternative Antibody Names Anti-G-Protein-Signaling Modulator 2 antibody
Anti-Mosaic Protein Lgn antibody
Anti-GPSM2 antibody
Anti-LGN antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance