• Immunohistochemical analysis of paraffin-embedded human Colon cancer. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 45min).

Anti-GPSM1 antibody (Internal) (STJ91508)

SKU:
STJ91508

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-G-protein-signaling modulator 1 (Internal) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
ELISA 1:5000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GPSM1
Gene ID: 26086
Uniprot ID: GPSM1_HUMAN
Immunogen Region: Internal
Specificity: AGS3 Polyclonal Antibody detects endogenous levels of AGS3 protein.
Immunogen: Synthesized peptide derived from the Internal region of human AGS3.
Post Translational Modifications Phosphorylation regulates interaction with G(i/o) alpha.
Function Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G-protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.
Protein Name G-Protein-Signaling Modulator 1
Activator Of G-Protein Signaling 3
Database Links Reactome: R-HSA-418594
Cellular Localisation Cytoplasm
Cytosol
Endoplasmic Reticulum Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Golgi Apparatus Membrane
Cell Membrane
Alternative Antibody Names Anti-G-Protein-Signaling Modulator 1 antibody
Anti-Activator Of G-Protein Signaling 3 antibody
Anti-GPSM1 antibody
Anti-AGS3 antibody

Information sourced from Uniprot.org

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