| Function | Orphan receptor involved in vision. Required for signal transduction through retinal depolarizing bipolar cells. Acts as an atypical G-protein coupled receptor that recruits and regulates the R7 group RGS-GNB5 complexes instead of activating G proteins: promotes the GTPase activator activity of R7 RGS proteins, increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Associates with components of metabotropic signaling cascade in retina ON-bipolar neurons, such as TRPM1 and GRM6: may control the ability of the GRM6 cascade to gate TRPM1. |
| Protein Name | Probable G-Protein Coupled Receptor 179Probable G-Protein Coupled Receptor 158-Like 1Gpr158-Like |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinPostsynaptic Cell MembraneCell ProjectionDendriteSpecifically Localizes To The Tips Of Retinal On-Bipolar Dendrites |
| Alternative Antibody Names | Anti-Probable G-Protein Coupled Receptor 179 antibodyAnti-Probable G-Protein Coupled Receptor 158-Like 1 antibodyAnti-Gpr158-Like antibodyAnti-GPR179 antibodyAnti-GPR158L antibodyAnti-GPR158L1 antibody |
Information sourced from Uniprot.org
