Host: |
Goat |
Applications: |
Pep-ELISA/WB/IF |
Reactivity: |
Human/Mouse/Rat/Cow |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Goat polyclonal antibody anti-GPR17 (C-Term) is suitable for use in ELISA, Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: |
0.5 mg/mL |
Dilution Range: |
WB-2-3µg/mlIF-Strong expression of the protein seen in the vesicles of HeLa cells and additionally in the plasma membrane of U251 cells. 10µg/mlELISA-antibody detection limit dilution 1:4000. |
Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: |
GPR17 |
Gene ID: |
2840 |
Uniprot ID: |
GPR17_HUMAN |
Immunogen Region: |
C-Term |
Accession Number: |
NP_005282.1 |
Immunogen Sequence: |
EGKTNESSLSAKSE |
Function | Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia. |
Protein Name | Uracil Nucleotide/Cysteinyl Leukotriene ReceptorUdp/Cyslt ReceptorG-Protein Coupled Receptor 17P2y-Like ReceptorR12 |
Database Links | Reactome: R-HSA-391906Reactome: R-HSA-416476Reactome: R-HSA-417957Reactome: R-HSA-418594 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Uracil Nucleotide/Cysteinyl Leukotriene Receptor antibodyAnti-Udp/Cyslt Receptor antibodyAnti-G-Protein Coupled Receptor 17 antibodyAnti-P2y-Like Receptor antibodyAnti-R12 antibodyAnti-GPR17 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance