Anti-GPR132 antibody (293-342 aa) (STJ93172)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human GPR132 at the amino acid range 293-342
General Information
| Short Description | Rabbit polyclonal anti-Probable G-protein coupled receptor 132 (293-342 aa) for use in WB, IF and ELISA in Human, Mouse and Monkey samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Monkey |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC-P 1:100-300ELISA 1:20000IF 1:100-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GPR132 |
| Gene ID | 29933 |
| Uniprot ID | GP132_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human GPR132 at the amino acid range 293-342 |
| Immunogen Region | 293-342 aa |
| Specificity | G2A Polyclonal Antibody detects endogenous levels of G2A protein. |
Additional Info
| Function | May be a receptor for oxidized free fatty acids derived from linoleic and arachidonic acids such as 9-hydroxyoctadecadienoic acid (9-HODE). Activates a G alpha protein, most likely G alpha(q). May be involved in apoptosis. Functions at the G2/M checkpoint to delay mitosis. May function as a sensor that monitors the oxidative states and mediates appropriate cellular responses such as secretion of paracrine signals and attenuation of proliferation. May mediate ths accumulation of intracellular inositol phosphates at acidic pH through proton-sensing activity. |
| Protein Name | Probable G-Protein Coupled Receptor 132G2 Accumulation Protein |
| Database Links | Reactome: R-HSA-373076Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinInternalized And Accumulated In Endosomal CompartmentsLpc Triggers The Relocalization From The Endosomal Compartment To The Cell Surface |
| Alternative Antibody Names | Anti-Probable G-Protein Coupled Receptor 132 antibodyAnti-G2 Accumulation Protein antibodyAnti-GPR132 antibodyAnti-G2A antibody |
Information sourced from Uniprot.org