| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GPN1 (255-374) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GPN1 |
| Gene ID: |
11321 |
| Uniprot ID: |
GPN1_HUMAN |
| Immunogen Region: |
255-374 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 255-374 of human GPN1 (NP_009197.2). |
| Immunogen Sequence: |
VGVSAVLGTGLDELFVQVTS AAEEYEREYRPEYERLKKSL ANAESQQQREQLERLRKDMG SVALDAGTAKDSLSPVLHPS DLILTRGTLDEEDEEADSDT DDIDHRVTEESHEEPAFQNF |
| Tissue Specificity | Expressed ubiquitously. |
| Function | Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import. Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation. May be involved in nuclear localization of XPA. |
| Protein Name | Gpn-Loop Gtpase 1Mbd2-Interacting ProteinMbdinRnapii-Associated Protein 4Xpa-Binding Protein 1 |
| Cellular Localisation | CytoplasmNucleusShuttles Between The Nucleus And The Cytoplasm |
| Alternative Antibody Names | Anti-Gpn-Loop Gtpase 1 antibodyAnti-Mbd2-Interacting Protein antibodyAnti-Mbdin antibodyAnti-Rnapii-Associated Protein 4 antibodyAnti-Xpa-Binding Protein 1 antibodyAnti-GPN1 antibodyAnti-MBDIN antibodyAnti-RPAP4 antibodyAnti-XAB1 antibodyAnti-HUSSY-23 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
