| Short Description : | Rabbit polyclonal GPN1 (255-374) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GPN1 |
| Gene ID: | 11321 |
| Uniprot ID: | GPN1_HUMAN |
| Immunogen Region: | 255-374 |
| Immunogen Sequence: | VGVSAVLGTGLDELFVQVTS AAEEYEREYRPEYERLKKSL ANAESQQQREQLERLRKDMG SVALDAGTAKDSLSPVLHPS DLILTRGTLDEEDEEADSDT DDIDHRVTEESHEEPAFQNF |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 255-374 of human GPN1 (NP_009197.2). |
| Tissue Specificity | Expressed ubiquitously. |
| Function | Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import. Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation. May be involved in nuclear localization of XPA. |
| Protein Name | Gpn-Loop Gtpase 1Mbd2-Interacting ProteinMbdinRnapii-Associated Protein 4Xpa-Binding Protein 1 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusShuttles Between The Nucleus And The Cytoplasm |
| Alternative Antibody Names | Anti-Gpn-Loop Gtpase 1 antibodyAnti-Mbd2-Interacting Protein antibodyAnti-Mbdin antibodyAnti-Rnapii-Associated Protein 4 antibodyAnti-Xpa-Binding Protein 1 antibodyAnti-GPN1 antibodyAnti-MBDIN antibodyAnti-RPAP4 antibodyAnti-XAB1 antibodyAnti-HUSSY-23 antibody |
Information sourced from Uniprot.org
