STJ72087 (0. 01µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer). Detected by chemiluminescence.

Anti-GPI/Neuroleukin antibody (Internal) (STJ72087)

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STJ72087-100
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Host: Goat
Applications: Pep-ELISA/WB/IHC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Goat polyclonal antibody anti-GPI/Neuroleukin (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: Peptide ELISA: antibody detection limit dilution 1:128000.
WB: Approx 60kDa band observed in Human Heart lysates (calculated MW of 63.1kDa according to NP_000166.2). Recommended concentration: 0.01-0.03µg/ml. Primary incubation was hour.
IHC:
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: GPI
Gene ID: 2821
Uniprot ID: G6PI_HUMAN
Immunogen Region: Internal
Accession Number: NP_000166.2
Immunogen Sequence: YREHRSELNLRR
Function In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion.
Protein Name Glucose-6-Phosphate Isomerase
Gpi
Autocrine Motility Factor
Amf
Neuroleukin
Nlk
Phosphoglucose Isomerase
Pgi
Phosphohexose Isomerase
Phi
Sperm Antigen 36
Sa-36
Database Links Reactome: R-HSA-5628897
Reactome: R-HSA-6798695
Reactome: R-HSA-70171
Reactome: R-HSA-70263
Cellular Localisation Cytoplasm
Secreted
Alternative Antibody Names Anti-Glucose-6-Phosphate Isomerase antibody
Anti-Gpi antibody
Anti-Autocrine Motility Factor antibody
Anti-Amf antibody
Anti-Neuroleukin antibody
Anti-Nlk antibody
Anti-Phosphoglucose Isomerase antibody
Anti-Pgi antibody
Anti-Phosphohexose Isomerase antibody
Anti-Phi antibody
Anti-Sperm Antigen 36 antibody
Anti-Sa-36 antibody
Anti-GPI antibody

Information sourced from Uniprot.org

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